International Circulation:  Could you please talk about the choice of optimal strategy of early antiplatelet therapy in patients with ACS?

《国际循环》：您能谈谈ACS患者早期抗血小板治疗的最佳策略选择吗？

Professor Mehta:  All patients with acute coronary syndrome should be treated with 600mg of clopidogrel and should be taken to the CATH lab for coronary angiography.  If they are a PCI candidate they should continue on 150mg daily for one week， in addition to aspirin.  It could be either high-dose aspirin or low-dose aspirin.  If they do not have a PCI then the dose should be dropped down to 75mg daily for the duration.  That should be the standard that we now use for clopidogrel therapy.

S R Mehta教授：所有ACS患者都应当给予600 mg氯吡格雷治疗，都应当被送入导管室行冠状动脉造影。如果患者拟行PCI，则除阿司匹林（可以是大剂量也可以是小剂量）之外，应继续应用氯吡格雷150 mg/d 1周。如果患者不行PCI治疗则剂量应减为75 mg/d 作为维持剂量。这应该是我们目前应用氯吡格雷治疗的标准方法。

 

S R Mehta简介
 
Shamir Mehta
BSc (Toronto)， MD (Toronto)， MSc (McMaster)， FRCPC
Associate Professor， Department of Medicine (Cardiology)
Associate Member， Dept of Clinical Epidemiology & Biostatistics
Director， Interventional Cardiology and Acute Coronary Syndrome Resea