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CADILLAC 试验:急性心肌梗死直接PCI后梗死相关动脉晚期再通、左心室功能与临床结局的关联
Relation between late patency of the infarct-related artery, left ventricular function, and clinical outcomes after primary percutaneous intervention for acute myocardial infarction (CADILLAC trial).
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 编辑:国际循环网 时间:2010/12/10 10:30:37    加入收藏
 关键字:CADILLAC 急性心肌梗死 直接PCI 梗死相关动脉晚期再通 左心室功能 临床结局 

    Halkin A, Aymong E, Cox DA, Mehran R, Lansky AJ, Fahy M, Weisz G, Garcia E, Tcheng JE, Grines CL, Stone GW.
    Cardiovascular Research Foundation and Lenox Hill Heart and Vascular Institute, New York, New York 10022, USA.
Abstract
    The importance of sustained patency of the infarct-related artery after primary percutaneous coronary intervention for acute myocardial infarction is controversial. We examined serial measures of left ventricular function and clinical outcomes in 280 patients with an initially occluded infarct artery in whom Thrombolysis In Myocardial Infarction trial grade 3 flow was achieved and routine follow-up angiography was performed 7 months after percutaneous coronary intervention. Reocclusion of the infarct artery was associated with decreased event-free survival, and the degree of restenosis was an independent predictor of the lack in improvement in left ventricular ejection fraction over time.

 

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